The TP63 gene located on chromosome 3q28 [1], encodes the tumor protein p63 (TP63 MIM*603273), belonging to the p53 transcription factor family [2], which is essential in the development of ectodermal structures comprising skin, sweat glands, hair, nails and teeth.
Weaning from mechanical ventilation in patients with artificial respiration is a complex process with a high impact on the patient's prognosis. Both its delay and its anticipation, and above all the failure in the process, have significant repercussions for the patient.